| Xenadrine EFX Extra Strength from Cytodyne, 120 caps
What is it?
New and Improved, Extra-Strength Xenadrine EFX is a potent ephedra free, thermogenic fat burner and lipolysis stimulator, proven to help break down fat. This revolutionary formula contains a powerful blend of natural ingredients shown in clinical research to increase the body’s metabolic rate and support the burning of body fat. (read xenadrine reviews at bottom of this page)
What Does it do?
Original Xenadrine EFX was the first scientifically based, ephedra free thermogenic (heat producing which leads to the body burning more calories) formula been shown to be truly effective in product specific clinical research. Now, New and Improved, Extra-Strength Xenadrine EFX is even better with the addition of Norambrolide™. This fermented sage compound has been shown in unpublished in-vitro research to increase levels of a cellular messenger called cAMP (cyclic adenosine monophosphate). The significance of this is that in some metabolic processes, cAMP is involved in activating cellular enzymes and other substances that help move fat out of the fat cells and promote the weight loss process; although no research has yet been done to demonstrate that Norambrolide™ will have this effect in humans. However, unpublished in-vitro research has shown that Norambrolide™ was successful at increasing lipolysis (the breakdown of fat) by 11-24%. Of course New and Improved, Extra-Strength Xenadrine EFX still provides all of the proven ingredients of the original formulation which was shown in clinical research to substantially increase resting energy expenditure and metabolic rate. These ingredients include green tea extract, which has been demonstrated in a randomized, placebo-controlled study to increase weight loss and burn calories. Other research on green tea has shown similar results. New and Improved, Extra-Strength Xenadrine EFX also contains bitter theobroma cacoa extract, a source theobromine. Theobromine and other related methylxanthines (e.g., caffeine) have been identified as having thermogenic activity in double-blind human and animal research. This advanced formula also contains Tyroplex™ and Isotherm™. Tyroplex™ is a proprietary blend of l-tyrosine and acetyl-l-tyrosine. Tyrosine is a precursor to catecholamines like norepinephrine and dopamine , which are integral to the body’s fat burning processes. Isotherm™ is a combination of the naturally-occurring flavones 3,3',4',5-7 pentahydroxyflavone (PF) and 3,3',4',7-tetrahydroxyflavone (TF). In in-vitro research both PF and TF9 11 have been shown to increase lipolysis (the breakdown of fat) and stimulate cyclic AMP accumulation. Rounding out this formula are vitamins C, B6, Pantothenic acid, Magnesium, and grape seed extract.
How do I Take it?
Take two capsules before breakfast or morning exercise session and two capsules at mid-afternoon.
Additional Notes: Do not exceed 4 capsules per day. Keep out of the reach of children. Not intended for persons under 18 years of age. Do not use if you are pregnant or nursing or at risk of or being treated for high blood pressure, heart disease, renal disease, hyperthyroidism, spasms, psychiatric disease, suffer from migraines, are allergic to tyramine or chocolate, have asthma, or are taking asthma medication. Consult your physician before use if you are taking a monoamine oxidase inhibitor (MAOI). The recommended dose of this product contains about as much caffeine as a cup of coffee and should not be taken by individuals wishing to eliminate caffeine from their diet. Limit use of caffeine-containing foods and beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness, and occasionally, rapid heartbeat.
Footnotes: Anonymous. Sclareolide Effect on cAMP in Two Cell Lines. Unpublished report by NovaScreen. 2003; 19 pp. Peele DM. Report on the Effects of Sclareolide. Unpublished report by Avoca, Inc. 2004; 3 pp. Kalman DS, et al. An Acute Clinical Trial to Evaluate the Safety of a Popular Commercial Weight Loss Supplement When used with Exercise. 2003 Experimental Biology Conference (FASEB) Abstract #83192, Board LB83. Kalman DS, et al. Efficacy of a commercial green tea extract/caffeine based product to increase basal metabolism in healthy adults. 2002 NIH/NIDDK The Interaction of Physical Activity and Nutrition: Biological Remodeling and Plasticity Conference. Dec. 8-10, 2002. Dulloo A, et al. Am J Clin Nutr 1999; 70:1040-5. Chantre P, et al. Phytomedicine 2002; 9:3-8. Bracco D, et al. American journal of physiology 1995; 269(4 Pt 1):E671-8. Dulloo AG, et al. Metabolism-clinical and experimental 1992; 41(11):1233-41. Green R. Human Hormones. New York: McGraw-Hill; 1970:55-61 Kuppusamy UR, Das NP. Potentiation of beta-adrenoceptor agonist-mediated lipolysis by quercetin and fisetin in isolated rat adipocytes. Biochemical pharmacology 1994; 47(3):521-9. Beretz A. Role of cyclic AMP in the inhibition of human platelet aggregation by quercetin, a flavonoid that potentiates the effect of prostacyclin. Biochemical pharmacology 1982; 31(22):3597-600. Kuppusamy UR, Das NP. Effects of flavonoids on cyclic AMP phosphodiesterase and lipid mobilization in rat adipocytes. Biochemical pharmacology 1992; 44(7):1307-15.
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Xenadrine EFX 
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